Does MRS Lactate Peak Correlate with Lactate in the CSF and Blood?

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Does MRS Lactate Peak Correlate with Lactate in the CSF and Blood?

Lactate cerebrospinal fluid (CSF) biochemical analysis is an invasive procedure routinely required during evaluation and monitoring of many neurological diseases. CSF lactate is considered an indicator of central nervous system cellular oxidative metabolism and many attempts have been made to set a reference limit of its concentration in children.1,2 CSF concentration may change within a short ...

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Lactate peak on brain MRS in children with syndromic mitochondrial diseases.

BACKGROUND Brain magnetic resonance spectroscopy (MRS) has been reported to be a valuable noninvasive tool in the diagnosis of some rare diseases. In this study, our aim was to assess lactate peak on single-voxel proton MRS in children with syndromic mitochondrial diseases (MDs). METHODS From March 2004 to November 2010, 14 patients who were diagnosed with syndromic MDs underwent single-voxel...

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The significance of elevated CSF lactate.

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ژورنال

عنوان ژورنال: Journal of Pediatric Neuroradiology

سال: 2015

ISSN: 1309-6680,1309-6745

DOI: 10.1055/s-0035-1564663